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Publications


Research papers      (* : corresponding author)


  • Fumiya Meguro, Hiroki Higashiyama, Yannick Pommery, Laura A. B. Wilson, Vuong Tan Tu, Taro Nojiri, Dai Fukui, Daisuke Koyabu*. The development of orofacial complex in bats: Implications for orofacial clefting. Journal of Anatomy. 【LINK】
  • Ryota Hayashi*, Hiroki Higashiyama, Koichi Goka (2024) Rethinking nomenclatural acts: Questions in taxonomy by the dedications to mythology and fictional monsters. BioScience, biae113 【LINK】
  • Banri Muramatsu, Daichi G. Suzuki, Masakazu Suzuki, Hiroki Higashiyama* (2023) Gross anatomy of the Pacific hagfish, Eptatretus burgeri, with special reference to the coelomic viscera. The Anatomical Record 307(1), 155-171. 【LINK】

  • Kaoru Mizukami, Hiroki Higashiyama*, Yuichiro Arima, Koji Ando, Norihiro Okada, Katsumi Kose, Shigehito Yamada, Jun K Takeuchi, Kazuko Koshiba-Takeuchi, Shigetomo Fukuhara, Sachiko Miyagawa-Tomita, Hiroki Kurihara* (2023) Coronary artery established through amniote evolution eLife 12:e83005. 【LINK/ eLife Science Digests/ Press release】

  • Tzu-Chin Chi, Fumiya Meguro, Masaki Takechi, Toshiko Furutera, Vuong Tan Tu, Hiroki Higashiyama, Joon Hyuk Sohn, Taro Nojri, Junpei Kimura*, Daisuke Koyabu* (2023) Anatomy and homology of the caudal auricular muscles in greater short-nosed fruit bat (Cynopterus sphinx). Journal of Veterinary Medical Science 23-0088. 【LINK】

  • Hiroki Higashiyama*, Daisuke Koyabu, Hiroki Kurihara (2023) Evolution of the therian face through complete loss of the premaxilla. Evolution & Development 25(1), 103-118. (Craniofacial Evo-Devo Special Issue; invited) 【LINK】
  • Hiroki Higashiyama*, Daisuke Koyabu, Tatsuya Hirasawa, Ingmar Werneburg, Shigeru Kuratani, Hiroki Kurihara (2021) Mammalian face as an evolutionary novelty. Proceedings of the National Academy of Sciences 118(44), e2111876118. 【LINK // PNAS In This Issue / Press release (UTokyo) / Press release (University of Tübingen)】
  • Taro Nojiri, Laura A. B. Wilson, Camilo López-Aguirre, Vuong Tan Tu, Shigeru Kuratani, Kai Ito, Hiroki Higashiyama, Nguyen Truong Son, Dai Fukui, Alexa Sadier, Karen E. Sears, Hideki Endo, Satoshi Kamihori, Daisuke Koyabu*. (2021) Embryonic evidence uncovers convergent origins of laryngeal echolocation in bats. Current Biology 31(7), 1353-1365.【LINK】
  • Tri H Vu, Masaki Takechi, Miki Shimizu, Taro Kitazawa, Hiroki Higashiyama, Akiyasu Iwase, Hiroki Kurihara, Sachiko Iseki*. (2021) Dlx5-augmentation in neural crest cells reveals early development and differentiation potential of mouse apical head mesenchyme. Scientific Reports 11(1), 1-15.【LINK】
  • Hiroki Higashiyama*, Yoshiakira Kanai. (2021) Comparative anatomy of the hepatobiliary systems in quail and pigeon, with a perspective for the gallbladder-loss. Journal of Veterinary Medical Science, 20-0669. 【LINK】
  • Hiromasa Yokoyama, Miho Yoshimura, Daichi G. Suzuki, Hiroki Higashiyama, Hiroshi Wada*. (2021) Development of the lamprey velum and implications for the evolution of the vertebrate jaw. Developmental Dynamics 250(1), 88-98.【LINK】
  • Montri Pattarapanawan, Mami Uemura, Nanae Miyazaki, Shohei Takami, Hirotaka Tomiyasu, Naoki Tsunekawa, Yoshikazu Hirate, Jun Fujishiro, Masamichi Kurohmaru, Masami Kanai-Azuma, Hiroki Higashiyama*, Yoshiakira Kanai*. (2020) Anatomical and histological characteristics of the hepatobiliary system in adult Sox17 heterozygote mice. The Anatomical Record 303(12), 3096-3107.【LINK】
  • Mami Uemura, Mayumi Higashi, Montri Pattarapanawan, Shohei Takami, Naoki Ichikawa, Hiroki Higashiyama, Taizo Furukawa, Jun Fujishiro, Yuki Fukumura, Takashi Yao, Tatsuro Tajiri, Masami Kanai-Azuma, Yoshiakira Kanai*. (2020) Gallbladder wall abnormality in biliary atresia of mouse Sox17+/− neonates and human infants. Disease Models & Mechanisms 13(4), dmm042119.【LINK】
  • Miki Shimizu, Nicolas Narboux-Nême, Yorick Gitton, Camille de Lombares, Anastasia Fontaine, Gladys Alfama, Taro Kitazawa, Yumiko Kawamura, Eglantine Heude, Lindsey Marshall, Hiroki Higashiyama, Youichiro Wada, Yukiko Kurihara, Hiroki Kurihara, Giovanni Levi*. (2018) Probing the origin of matching functional jaws: roles of Dlx5/6 in cranial neural crest cells. Scientific Reports 8(1), 1-15.【LINK】
  • Hitomi Igarashi, Mami Uemura, Ryuji Hiramatsu, Ryuto Hiramatsu, Saki Segami, Montri Pattarapanawan, Yoshikazu Hirate, Yuki Yoshimura, Haruo Hashimoto, Hiroki Higashiyama, Hiroyuki Sumitomo, Masamichi Kurohmaru, Yukio Saijoh, Hiroshi Suemizu, Masami Kanai-Azuma, Yoshiakira Kanai*. (2018) Sox17 is essential for proper formation of the marginal zone of extraembryonic endoderm adjacent to a developing mouse placental disk. Biology of Reproduction 99(3), 578-589.【LINK】
  • Hiroki Higashiyama*, Mami Uemura, Hitomi Igarashi, Masamichi Kurohmaru, Masami Kanai-Azuma, Yoshiakira Kanai. (2018) Anatomy and development of the extrahepatic biliary system in mouse and rat: a perspective on the evolutionary loss of the gallbladder. Journal of Anatomy 232(1), 134-145.【LINK】
  • Hiroki Higashiyama, Aisa Ozawa, Hiroyuki Sumitomo, Mami Uemura, Ko Fujino, Hitomi Igarashi, Kenya Imaimatsu, Naoki Tsunekawa, Yoshikazu Hirate, Masamichi Kurohmaru, Yukio Saijoh, Masami Kanai-Azuma, Yoshiakira Kanai*. (2017) Embryonic cholecystitis and defective gallbladder contraction in the Sox17-haploinsufficient mouse model of biliary atresia. Development 144(10), 1906-1917.【LINK】
  • Hiroki Higashiyama*, Tatsuya Hirasawa, Yasuhiro Oisi, Fumiaki Sugahara, Susumu Hyodo, Yoshiakira Kanai, Shigeru Kuratani. (2016) On the vagal cardiac nerves, with special reference to the early evolution of the head-trunk interface. Journal of Morphology 277(9), 1146-1158.【LINK】
  • Hiroki Higashiyama*, Aisa Ozawa, Hiroyuki Sumitomo, Mami Uemura, Ko Fujino, Hitomi Igarashi, Kenya Imaimatsu, Naoki Tsunekawa, Yoshikazu Hirate, Masamichi Kurohmaru, Yukio Saijoh, Masami Kanai-Azuma, Yoshiakira Kanai. (2016) Anatomy of the Murine Hepatobiliary System: A Whole-Organ-Level Analysis Using a Transparency Method. The Anatomical Record 299(2), 161-172.【LINK】
  • Hiroki Higashiyama, Shigeru Kuratani*. (2014) On the maxillary nerve. Journal of Morphology 275(1) 17-38.【LINK】


Under review, Pre-prints      (* : corresponding author)


  • [preprint] Akiyasu Iwase, Yasunobu Uchijima, Daiki Seya, Mayuko Kida, Hiroki Higashiyama, Kazuhiro Matsui, Akashi Taguchi, Shogo Yamamoto, Shiro Fukuda, Seitaro Nomura, Takahide Kohro, Chisa Shukunami, Haruhiko Akiyama, Masahide Seki, Yutaka Suzuki, Youichiro Wada, Hiroyuki Aburatani, Yukiko Kurihara, Sachiko Miyagawa-Tomita, Hiroki Kurihara* (2022) Cardiac neural crest lineage diversity and underlying gene regulatory networks revealed by multimodal analysis. bioRxiv doi: https://doi.org/10.1101/2022.06.23.497419 【LINK】



Books

  • Hiroki Higashiyama*, Yoshiakira Kanai (2019) Chapter: Biliary system; anatomy and development. in Kuipers E eds. Encyclopedia of Gastroenterology 2nd Edition. Elsevier ISBN:978-0128124604【LINK】


Misc.

  • 東山大毅　"口唇口蓋裂に表れる進化の足跡"　『医学のあゆみ』 290巻1号　"かたちづくり"を制御する分子メカニズム　2024年　【LINK】
  • 東山大毅.　哺乳類の顔面の進化 in 特集：形態進化研究最前線『生物の科学 遺伝 』 78( 1 ). 2024年 【LINK】
  • 東山 大毅　シンポジウムリポート「S09：新機軸を生む形態進化をどう理解するか」日本進化学会ニュース 24(3) 7-8 2023年
  • RESEARCH 哺乳類の鼻をつくった顔の進化　JT生命誌研究館 季刊「生命誌」113号　2023年6月1日【LINK】
  • 東山 大毅　学会賞受賞記 研究奨励賞「闇夜の森で虎を描くように」日本進化学会ニュース 24(1) 22-25. 2023年
  • 東山大毅　「進化的新機軸としての哺乳類の顔」生体の科学 73( 3 ) 272-277. 2022年
  • 東山大毅　シンポジウム「進化の方向性と形態進化のみらい」開催報告.  新学術領域研究「進化の制約と方向性〜微生物から多細胞生物までを貫く表現型 進化原理の解明〜」ニュースレター 5(5) 2021年9月13日
  • 東山大毅　顔は発生原基の組合せ : 哺乳類の鼻は爬虫類の口先. 新学術領域「進化の制約と方向性」ニュースレター 4(4)「シンポジウム「表現型進化を制約しうる発生基盤」開催報告　 2020 年 9 月
  • 東山 大毅　Making of mammalian face by drastic shift of facial processes 顔面原基の劇的なシフトが哺乳類の顔を作った. 新学術領域研究「進化の制約と方向性～微生物から多細胞生物までを貫く表現型 進化原理の解明～」ニュースレター 2(4) 14 2018 年 8 月
  • 東山 大毅　「The 1st AsiaEvo Conference 参加記」 新学術領域研究「進化の制約と方向性～微生物から多細胞生物までを貫く表現型 進化原理の解明～」ニュースレター 2(2) 40-42 2018 年 6 月
  • 東山 大毅　大会シンポジウムレポート　"S4進化における発生の役割 " 日本進化学会ニュース 17(3) 8-10 2016年